Screening and Profiling

Evaluate lead compounds with our biochemical and cell-based screening services. Save time by letting us screen your compounds of interest against our unique assay panels or determine IC50 values. With our portfolio of >600 assays available as a service, we’re here to help advance your drug discovery program.

Our biochemical-based screening services provide excellent tools to quickly identify potential therapeutics, predict potency, and narrow down a large pool of candidates to a much smaller one.

To gain insight on cellular functional interventions, we also offer cell-based screening services. The cell-based data offers a more comprehensive view of the biological context and the resulting cellular responses, allowing for more informed decisions to be made about which compounds to advance to development.

We are Uniquely Positioned for Your Discovery

  • Extensive Immunotherapy panels, including many unique immunotherapy targets
  • First commercially available and largest histone demethylase panel
  • Over 20 unique histone methyltransferases
  • Extensive SARS-CoV-2 assays, including 3CL Protease, RdRp, Papain-like Protease, and Spike:ACE2 binding assays.
  • Complete PARP isozyme panel and unique PARP-trapping assays
  • Largest phosphodiesterase isozyme panel
  • First complete suite of HDAC and SIRT enzymes
  • Extensive bromodomain and HSP90 panels

Our Deliverables to You

 

Detailed Results

Extensive report with raw and analyzed data, graphs, and detailed protocols. Typically includes positive controls for inhibition.

Fast Turnaround

Receive results within weeks after our receipt of your compounds.

Quality & Consistency

Proteins and enzymes synthesized and QC’d in-house to ensure the highest level of inter- and intra-assay consistency.

Extensive Selection

Choose from over 700 in-house developed assays, including many novel assay kits.

Platform Options

Choose the format that works best for your experiment or perform orthogonal testing on multiple platforms to verify your results.

Expertise

Dedicated, expert screening team

Custom Product Development

Can’t find the product you are looking for? Our experts could build it for you. Learn more.

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